Welcome to the Skokowa-Welte Lab

The Division of Translational Oncology is a multidisciplinary team that is part of the Department of Internal Medicine II at the University Hospital Tübingen. Our group studies blood disorders, such as inherited bone marrow syndromes and leukemia. Using cutting-edge techniques and different experimental models, we investigate hematopoietic stem and progenitor cells (HSPC) under normal and pathological conditions in order to understand their malignant transformation. Our goals are to identify key players, e.g., gene mutations and signaling pathways, involved in disease development and to further apply our knowledge towards the development and establishment of novel therapies for patients.

Our main research topics are:

Disease Modeling

Leukemogenesis

Gene Therapy

Protein design